Asian Journal of Research and Reports in Gastroenterology

A Literature Review: Adjunctive Use of Proton Pump Inhibitors to Variceal Band Ligation in Cirrhotic Patients

Samar Mohamed Osman Ahmed Musa *

University of Khartoum, Saudi Arabia and Department of Clinical Pharmacy, University of Gezira, Saudi Arabia.

Moawia El Balal Mohamed

Faculty of Medicine, University of Gezira, Saudi Arabia.

*Author to whom correspondence should be addressed.

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Abstract

Introduction: This review focuses on the effect of Proton pump inhibitors (PPIs), acid-suppressive agents, combined with ligation to manage rebleeding ulcers in cirrhotic patients.

Methods: Data reviewed during approximately the last 20 years combining different studies concerning the use of antiacids in Variceal Cirrhotic Patients.

Result: Data showed different results, with most supporting the role of PPIs in this field.

Conclusion: PPIs used as adjunctive to EVL in cirrhotic patients for either prophylaxis or treatment of bleeding ulcers following ligation showed successful results and a good impact on general health and should be tried on those patients to improve their care.

Keywords: Acid suppression, ligation ulcer, PPI, varies

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