A Literature Review: Adjunctive Use of Proton Pump Inhibitors to Variceal Band Ligation in Cirrhotic Patients
Published: 2023-09-06
Page: 112-116
Issue: 2023 - Volume 6 [Issue 1]
Samar Mohamed Osman Ahmed Musa *
University of Khartoum, Saudi Arabia and Department of Clinical Pharmacy, University of Gezira, Saudi Arabia.
Moawia El Balal Mohamed
Faculty of Medicine, University of Gezira, Saudi Arabia.
*Author to whom correspondence should be addressed.
Abstract
Introduction: This review focuses on the effect of Proton pump inhibitors (PPIs), acid-suppressive agents, combined with ligation to manage rebleeding ulcers in cirrhotic patients.
Methods: Data reviewed during approximately the last 20 years combining different studies concerning the use of antiacids in Variceal Cirrhotic Patients.
Result: Data showed different results, with most supporting the role of PPIs in this field.
Conclusion: PPIs used as adjunctive to EVL in cirrhotic patients for either prophylaxis or treatment of bleeding ulcers following ligation showed successful results and a good impact on general health and should be tried on those patients to improve their care.
Keywords: Acid suppression, ligation ulcer, PPI, varies