Management of Gastrointestinal Stromal Tumors: Experience of a University Hospital

Main Article Content

Driss Erguibi
Ettaoussi Abdelhak
Asmar Mohamed
Saâd Rifki Jai
Rachid Boufettal
Farid Chehab

Abstract

Gastrointestinal stromal tumors or GISTs are rare tumors: 1 to 3% of malignant tumors gastrointestinal. 65% of these tumors sit in the stomach, 25% in the small bowel, 5-10% in the colon-rectum...

They occur secondary to activating mutations of the KIT or PDGFRA receptors. In 85% of cases, and are diagnosed at a localized stage in about 85% of cases. The spontaneous recurrence rate for patients who have undergone surgery and have a complete resection is approximately 40% at 10 years.

In this article we present a case of a gregarious stromal tumor whose age of occurrence was early and recurrence after complete surgical resection and targeted therapy was rapid and aggressive.

Also we discuss in the light of the literature, the results, surgical treatment, targeted therapy, histological findings and prognostic factors on which the risk of recurrence depends.

Keywords:
Gastrointestinal stromal tumors (GIST), pathogenic factors, prognosis, early recurrence.

Article Details

How to Cite
Erguibi, D., Abdelhak, E., Mohamed, A., Jai, S. R., Boufettal, R., & Chehab, F. (2020). Management of Gastrointestinal Stromal Tumors: Experience of a University Hospital. Asian Journal of Research and Reports in Gastroenterology, 4(1), 8-13. Retrieved from https://journalajrrga.com/index.php/AJRRGA/article/view/30123
Section
Case Study

References

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