Caroli’s Disease Revealed by Acute Pancreatitis and Angiocholitis: Case Report

Main Article Content

Abdelilah El Bakouri
Abderrahmane Lamnaouar
Othmane Elyamine
Mounir Bouali
Khalid Elhattabi
Fatimazahra Bensardi
Abdelaziz Fadil


Background: Caroli's disease (CD) is a rare congenital disorder. The early diagnosis of the disease and differentiation of types I and II are of extreme importance to patient survival. This case report was designed to review, discuss to clarify the clinical characteristics of the disease.

Methods: The demographic and clinical feature, laboratory indicators, imaging findings and pathology results were reviewed.

Results: Caroli's disease can occur at any age specially young age. Magnetic resonance cholangiopancreatography (MRCP) and computed tomography (CT) examinations were most useful in diagnosing CD.

Conclusions: No typical symptoms, signs or laboratory indicators are able to distinguish CD from other conditions. Both MRI and CT were most valuable in diagnosis.

Caroli's disease (CD, MRI, CT scan), chronic smoker.

Article Details

How to Cite
Bakouri, A. E., Lamnaouar, A., Elyamine, O., Bouali, M., Elhattabi, K., Bensardi, F., & Fadil, A. (2020). Caroli’s Disease Revealed by Acute Pancreatitis and Angiocholitis: Case Report. Asian Journal of Research and Reports in Gastroenterology, 4(2), 1-5. Retrieved from
Case Study


Caroli J, Soupault R, Kossakowski J, et al. Congenital polycystic dilation of the intrahepatic bile ducts; attempt at classification. La semaine des hopitaux: organe fonde par l'Association d'enseignement medical des hopitaux de Paris. 1958;34(8/2)488.

Fulcher AS, Turner MA, Sanyal AJ. Case 38: Caroli disease and renal tubular ectasia. Radiology. 2001;220:720– 723.

Caroli J. Diseases of the intrahepatic biliary tree. Clin Gastroenterol. 1973;2:147–161.

Bettini G, Mandrioli L, Morini M. Bile duct dysplasia and congenital hepatic fibrosis associated with polycystic kidney (Caroli syndrome) in a rat. Vet Pathol. 2003;40:693–694.

De Tommaso AM, Santos DS, Hessel G. Caroli's disease: 6 case studies. Acta Gastroenterol Latinoam. 2003;33:47–51.

Desmet J. Pathogenesis of ductal plate abnormalities. Mayo Clin Proc. 1998;73:80–89.

Wu KL, Changchien CS, Kuo CM, Chuah SK, Chiu YC, Kuo CH. Caroli's disease – a report of two siblings. Eur J Gastroenterol Hepatol. 2002;14:1397–1399.

Ozlem Y, Yusuf B. Clinical characteristics of Caroli's disease. World J Gastroenterol. 2007;13:1930–1933.

Wang, Zhong‐Xia, LI, Yong‐Gang, Wang, Rui‐Lin, et al. Clinical classification of Ca roli's disease: an analysis of 30 patients. HPB. 2015;17(3) :278-283.

Kassahun WT, Kahn T, Wittekind C, Mossner J, Caca K, Hauss J et al. Caroli's disease: liver resection and liver transplantation. Experience in 33 patients. Surgery. 2005;138:888–898.

Desmet VJ. Pathogenesis of ductal plate malformation. JGastroenterol Hepatol. 2004;19(Suppl.):356–360.