Ulcerative Colitis in Children at Campus Teaching Hospital of Lome-Togo: A Report of Two Cases
Asian Journal of Research and Reports in Gastroenterology,
Page 1-4
Abstract
Introduction: Ulcerative colitis is one of the chronic inflammatory bowel diseases which, together with Crohn's disease. We aimed to report the first cases of ulcerative colitis in two children in Togo and describe their diagnostic and therapeutic course.
Result: The first case concerned a 30-month-old infant brought in by his parents was admitted for glairo-sanguinous diarrhea that had been evolving for 13 months before the consultation. The parents consulted general practitioners and pediatricians on several occasions without success. Total colonoscopy with biopsies and their anatomopathological examination were in favor of ulcerative colitis. The blood test for ASCA was negative and for pANCA positive. The second case concerned a 12-year-old teenager accompanied by his mother and was seen in consultation for daily rectal bleeding evolving since the age of about 7 years, which sprays the toilet bowl regardless of the consistency of the stools. Total colonoscopy with biopsies and their anatomopathological examination noted a rectal mucosa with slight chronic inflammatory changes without specificity. The blood test for ASCA was negative and that of pANCA positive. The two patients were put on mesalamine with a good evolution under treatment.
Conclusion: UC should be rapidly evoked in children and infants presenting symptoms such as rectal bleeding and chronic diarrhea in order to ensure early diagnosis and care.
Keywords:
- Children
- inflammatory bowel disease
- Togo
- ulcerative colitis.
How to Cite
References
Loftus E.V. Clinical epidemiology of inflammatory bowel disease: incidence, prevalence and environmental influences. Gastroenterology. 2004;126:1504-17.
Moline F., Gower-Rousseau C., Yzet T. et al. Opposite evolution in incidence of Crohn’s desease and ulcerative colitis in Northen france (1988-1999). Gut. 2004; 53:843-8.
Alese OB, Irabor DO. Pyoderma gangrenosum and ulcerative colitis in the tropics. Rev Soc. Bras. Med. Trop. 2008; 41:6647.
5-Bagny A, Akolly DAE, Kogoe LRM, Djadou KE. A girl with Crohn’s disease in a tertiary care hospital of Togo: A Case Report. Asian Journal of Research and Reports in Gastroenterology. 2021;5(1): 28-31
Jean-Frédéric C, Gwenola VM, Antoine C, Gower-Rousseau C, et al. Jean-louis S. Épidémiologie et facteurs de risque des maladies inflammatoires chroniques de l’intestin. Bull. Acad. Natle Med. 2007; 191:1105-1123.
Sach SC, Khalili H, Gower-Rousseau C, Olen O, Benchimol EI, Lynge E, et al. Sex-based differences in incidence of inflammatory bwel diseases-pooled analysis of population-based studies from western countries. Gastroenterology. 2018; 155(4):1079-89.
POST U. Hugot JP, Viala J. Physiopathologie de la maladie de Crohn: l’indispensable pour le clinicien. 2015;181-8.
Jostins L, Ripke S, Weersma RK, et al. Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease. Nature. 2012;491(7422):119-24.
Ahmad T, Tamboli CP, Jewell D, Colombel JF. Clinical relevance of advances in genetics and pharmacogenetics of IBD. Gastroenterology. 2004;126:1533-49.
Gower-Rousseau C, Leryer A, Génin M, et al. Epidémiologie descriptive et évolution dans le temps et l’espace de l’incidence des maladies inflammatoires chroniques intestinales dans le nord-ouest de la France (1988-2014). Bull Epidémiol Hebd. 2019;(13):228-36.
Bougouma A, Sombié R, Goumbri-Lompo O, Ido-Da TRC, Zoure N, Darankoum D et al. La rectocolite hémorragique chez le noir africain. Analyse de 20 cas au Burkina Faso. J. Afr. Hépatol. Gastroentérol. 2010; 4:147-151.
Hyams J, Crandall W, Kugathasan S, Griffiths A, Olson A, Johanns J, et al. Reach Study Group. Induction and maintenance infliximab therapy for the treatment of moderate-to-severe Crohn’s disease in children. Gastroenterology. 2007132(3): 863-73
Day AS, Whitten KE, Sidler M, Lemberg DA. Systematic review: nutritional therapy in paediatric Crohn’s disease. Aliment Pharmacol Ther. 2008;27(4):293-307.
-
Abstract View: 58 times
PDF Download: 29 times
