Asian Journal of Research and Reports in Gastroenterology 2020-10-09T05:17:09+00:00 Asian Journal of Research and Reports in Gastroenterology Open Journal Systems <p style="text-align: justify;"><strong>Asian Journal of Research and Reports in Gastroenterology</strong>&nbsp;aims to publish&nbsp;high-quality&nbsp;papers (<a href="/index.php/AJRRGA/general-guideline-for-authors">Click here for Types of paper</a>) in all areas of&nbsp;‘Gastroenterology’. This journal facilitates the research and wishes to publish papers as long as they are technically correct, scientifically motivated. The journal also encourages the submission of useful reports of negative results. This is a quality controlled,&nbsp;OPEN&nbsp;peer-reviewed, open access INTERNATIONAL journal.</p> <p style="text-align: justify;">&nbsp;</p> Management of Gastrointestinal Stromal Tumors: Experience of a University Hospital 2020-09-26T10:30:00+00:00 Driss Erguibi Ettaoussi Abdelhak Asmar Mohamed Saâd Rifki Jai Rachid Boufettal Farid Chehab <p>Gastrointestinal stromal tumors or GISTs are rare tumors: 1 to 3% of malignant tumors gastrointestinal. 65% of these tumors sit in the stomach, 25% in the small bowel, 5-10% in the colon-rectum...</p> <p>They occur secondary to activating mutations of the KIT or PDGFRA receptors. In 85% of cases, and are diagnosed at a localized stage in about 85% of cases. The spontaneous recurrence rate for patients who have undergone surgery and have a complete resection is approximately 40% at 10 years.</p> <p>In this article we present a case of a gregarious stromal tumor whose age of occurrence was early and recurrence after complete surgical resection and targeted therapy was rapid and aggressive.</p> <p>Also we discuss in the light of the literature, the results, surgical treatment, targeted therapy, histological findings and prognostic factors on which the risk of recurrence depends.</p> 2020-09-26T00:00:00+00:00 ##submission.copyrightStatement## Pancreatic Neuroendocrine Tumor Associated with Pancreatic Adenocarcinoma: A Case Report and Review of the Literature 2020-10-05T05:58:57+00:00 Asmar Mohamed Ettaoussi Abdelhak Saâd Rifki Jai Driss Erguibi Rachid Boufettal Farid Chehab <p>Pancreatic adenocarcinoma (PAC) is a high mortality cancer. Age, nicotine exposure, obesity, old-onset type 2 diabetes and chronic pancreatitis are identified risk factors for PAC. The Peutz-Jeghers Syndrome, Atypical Familial Syndrome of Multiple Moles and Melanomas (AFSMMM), Hereditary Ovarian and Breast Cancer, HNPCC and Familial Adenomatous Polyposis are the major genetic syndromes at high risk for pancreatic cancer. Neuroendocrine tumours (NETs) are defined by the expression of structural proteins and hormonal products common to neurons and endocrine cells. There is no identified risk factor for pancreatic NETs other than genetic predisposition syndromes (multiple endocrine neoplasia type 1 [MEN1], von Hippel-Lindau syndrome, tuberous sclerosis [TBS]). In this article we present a case of pancreatic neuroendocrine tumor associated with pancreatic adenocarcinoma and we discuss in light of the data in the literature, the risk factors that expose to both types of pancreatic tumors).</p> 2020-10-05T00:00:00+00:00 ##submission.copyrightStatement## A Giant Ovarian Cyst Hernia from an Abdominal Incision: A Case Report and Review of the Literature 2020-10-09T05:17:09+00:00 Asmar Mohamed Elazhari Abdessamad Elkarouachi Asmaa Rifki Jai Driss Erguibi Rachid Boufettal Farid Chehab <p>We report a case of a giant ovarian cyst hernia from an abdominal incisional surgery patient, she underwent resection of the giant cyst and benefited of a cure for eventration with a polypropylene mesh.</p> 2020-10-09T00:00:00+00:00 ##submission.copyrightStatement## The COVID-19 Outbreak Action Plan for Endoscopy Services in a Tertiary Hospital in East Malaysia 2020-09-12T06:03:00+00:00 James Emmanuel Nagaraj Sriram Raman Muthukaruppan <p>The COVID-19 Pandemic continues to evolve and its effects will leave a lasting impact on all levels of health care delivery system long after the dust settles. The Endoscopy unit which is an integral component of gastroenterology services has been recognised as a potential portal of transmission with prospective ascertainment of endoscopist exposure to infectious particles during GI procedures. The State of Sabah recorded its first COVID-19 positive case on March 12<sup>th</sup>, 2020. To date there has been a total number of 402 confirmed cases and 8 deaths recorded in this state. At our Endoscopy unit, a new Action Plan was introduced to the existing framework as a response measure to ameliorate the risk of nosocomial transmission. The strategies drawn up were predicated on local statistics of clinical presentation, recognised mode of transmission and clinical urgency of performing a procedure. Postponement of all elective cases at our unit was a major decision justified by reports of community spread of COVID-19 infection. Local data which disclosed a large proportion of asymptomatic COVID-19 patients, were a crucial factor in our decision to subject every patient under the semi urgent list to RT-PCR testing prior to an endoscopic procedure. These policies were executed with the objective of protecting our workforce and minimising the risk of nosocomial transmission in the unit. Though it may not address every clinical eventuality, our aim with these risk management strategies, is to maintain zero percent infection while continuing to provide optimal endoscopy services.</p> 2020-09-12T00:00:00+00:00 ##submission.copyrightStatement## Gastro - Protective Effect of Grewia optiva (Dhamna) Leaf Extract on Ethanol Induced Gastric Ulcer in Rats 2020-10-09T04:55:50+00:00 Saira Aslam Muhammad Aslam Tahir Muhammad S. A. Abbasi <p>In present examination, gastro defensive movement of <em>Grewia optiva</em> (GO) in rodents has been explored based on bioactive mixes (tannins, terpenoids, flavonoids, steroids and saponins) present in it. Ethanolic concentrate of <em>Grewia optiva</em> leaves was utilized in present study to research its gastro-defensive impact on ethanol actuated gastric ulcer in Albino rats. The investigation including negative, positive, drug, and reference controls.</p> 2020-10-09T00:00:00+00:00 ##submission.copyrightStatement##