Asian Journal of Research and Reports in Gastroenterology

Atypical Manifestation of IgG-4 Related Disease as Space Occupying Lesion Mimicking Hepatocellular Carcinoma in a Renal Transplant Recipient

Kiran Bajaj

Department of Gastroenterology and Hepatology, Sindh Institute of Urology and Transplantation, Pakistan.

Raja Taha Yaseen Khan *

Department of Gastroenterology and Hepatology, Sindh Institute of Urology and Transplantation, Pakistan.

Shoaib Ahmed Khan

Department of Gastroenterology and Hepatology, Sindh Institute of Urology and Transplantation, Pakistan.

Zain Majid

Department of Gastroenterology and Hepatology, Sindh Institute of Urology and Transplantation, Pakistan.

Nasir Mehmood

Department of Gastroenterology and Hepatology, Sindh Institute of Urology and Transplantation, Pakistan.

Muhammad Ali Khalid

Department of Gastroenterology and Hepatology, Sindh Institute of Urology and Transplantation, Pakistan.

Abbas Ali Tasneem

Department of Gastroenterology and Hepatology, Sindh Institute of Urology and Transplantation, Pakistan.

Syed Mudassir Laeeq

Department of Gastroenterology and Hepatology, Sindh Institute of Urology and Transplantation, Pakistan.

Nasir Hasan Luck

Department of Gastroenterology and Hepatology, Sindh Institute of Urology and Transplantation, Pakistan.

*Author to whom correspondence should be addressed.

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Abstract

IgG₄-related disease (IgG_4-RD) is a multisystem fibro-inflammatory condition mostly prevalent in older males. The cornerstone for the treatment of IgG₄ related disease is Corticosteroids.It rarely affects immunosuppressive population such as solid organ transplantation. Here we present to you a case of a young lady with a history of renal transplantation evaluated for symptoms of abdominal pain and weight loss and was diagnosed as a case of IgG₄ related liver disease on the basis of liver lesion biopsy.

Keywords: Immunosuppressants, hepatocellular carcinoma, fibroinflammation, weight loss, abdominal pain

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